Major Accomplishments of KIST Over Its 40-Year History. Since its foundation over 40 years ago, KIST has remained faithful to its role as a comprehensive research institute supporting Korea's interests and has made active contributions to the growth of the nation's industrial base through advancements in science and technology. A review of its major accomplishments through the years offer a peek into the most significant events in its history.

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Project Name Real-time in vivo imaging of the beating mouse heart at microscopic resolution
Year 2012 Director Dr. Lee Sung On

Real-time in vivo imaging of the beating mouse heart at microscopic resolution

1. Content &Characteristic

O Real-time imaging of moving organs and tissues at microscopic resolutions represents a major challenge in studying the complex biology of live animals

O A technique based on a novel stabilizer setup combined with a gating acquisition algorithm for the imaging of a beating murine heart at the single-cell level has been developed

O This method allows serial in vivo fluorescence imaging of the beating heart in live mice over the course of several hours.




2. Scientific Value

O This method is expected to facilitate the study of various heart diseases and eventually to help the development of novel treatment to them.

O This generic method could be adapted to other moving organs and thur broadly facilitate in vivo microscopic investigations

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