Major Accomplishments of KIST Over Its 40-Year History. Since its foundation over 40 years ago, KIST has remained faithful to its role as a comprehensive research institute supporting Korea's interests and has made active contributions to the growth of the nation's industrial base through advancements in science and technology. A review of its major accomplishments through the years offer a peek into the most significant events in its history.

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Project Name Development of an Analysis Method for Amphetamine
Year 2007 Director Dr. Dong Hyun KIM
○ Content & Characteristic
  - In vitro research regarding metabolism of dimethylamphetamine(DMA)
  - It verified that DMA is metabolized as methylamphetamine(MA), parahydroxyamphetamine
    (p-hydroxy DMA) and dimethylamphetaminenoxide(DMA-N-oxide).
  - CYP2D6 and FMO1 are related to metabolism of DMA.
  - The speed of d-DMA metabolism is faster than 1-DMA.
  - Establishment of the concurrent analysis method for DMA, MA, AM, p-hydroxy DMA,
     p-hydroxy MA, p-hydroxy AM and DMA-n-oxide.

○ Scientific Value
  - Development of a new analytical system for the amphetamine class.
  - Development of a distinction method to find out the misused drug substance.
○ Economic Effect
  - This method can be transferred to laboratories which performs drug tests including the
     Supreme Prosecutor's Office.
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