• Chemical Biology Group4

    Chemical Biology Group4

    Date 2015-03-27

  • Chemical Biology Group3

    Chemical Biology Group3

    Date 2015-03-27

  • Chemical Biology Group2

    Chemical Biology Group2

    Date 2015-03-27

  • Chemical Biology Group1

    Chemical Biology Group1

    Date 2015-03-27

  • Kist

    Kist

    Date

  • Chemical Biology Group4
  • Chemical Biology Group3
  • Chemical Biology Group2
  • Chemical Biology Group1
  • Kist
이전사진 다음사진

Knowledge-Based Drug Design and Synthesis (Medicinal Chemistry)

  • SbDD: Drug design based on x-ray crystal structures of target proteins and homology model building using various in silico tools.
  • LbDD: Ligand-based drug design based on pharmacophore approach.
  • Lead optimization through repetitive process of efficacy screening and scaffold modification.
  • Research on novel organic reactions and synthetic compound libraries.

Bioactive Molecules Screening

  • Functional assay techniques for monitoring GPCR and ion channels using FDSS6000 (multi-plate reader).
  • High-throughput screening techniques for electrophysiologically active molecules using Patchliner (multi-channel automated patch clamp).
  • Development of enzyme- and cell-based assay systems for screening selected kinase inhibitors as anti-cancer drugs.
  • Evaluation and assesment of bioactive molecules through cell-based assay.
  • Platform technology development of various in vitro assays and protocols.

Chemical Biology

  • Discovery and evaluation of novel targets for drug development based on molecular mechanistic studies of diseases.
  • Path-breaking technologies on early and innovative targets.
  • Research focusing on diseases with highly unmet need.

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