Research Fields of KIST Professors

research fields list
Name Song, Eun Joo
Position(full time/adjunct) Full time Professor
KIST School Major Bio-Medical Science and Technology
Division / Center Materials and Life Science Research Division / Molecular Recognition Research Center
Email ejsong@kist.re.kr
Telephone +82-2-02-958-5086


Research Field & Research Interest


Research Project
  • Target identification via understanding splicing regulation by structural and functional analysis
  • Development of analytical method for miRNA profiling in cancer using nanoparticle
  • Development of analytical method for miRNA using nanoparticle
  • Study of interacting proteins and functional mechanism of Usp15
  • The functional role of deubiquitinating enzymes in cell division
  • Regulation of cell division by ubiquitin system
  • Studies on regulatory network of cell division
  • Regulation of cell proliferation and division by post-translational modification
  • Identification of anticancer target by functional regulation of Usp4
  • Study of calcium signaling associated proteins and metabolites for systems biology
  • Development of culture and co-culture system for retinal cells
  • Functional studies of deubiquitinating enzyme in the cellular signaling pathway


Paper Publication
Paper Publication
Title Author Journal Date Abstract
Oxidative modification of nucleoside diphosphate kinase and its identification by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry 송은주,Yang Sun Kim,Ji Young Chung,Eunhee Kim,Suhn-Kee Chae,Kong-Joo Lee, Biochemistry 200008
Proteomic analysis of protein phosphorylations in heat shock response and thermotolerance Hee-Jung Kim,송은주,Kong-Joo Lee, The Journal of biological chemistry 200206
Human Fas-associated factor 1 interacts with heat shock protein 70 and negatively regulates chaperone activity 김희정,송은주,이윤석,김은희,이공주, The Journal of biological chemistry 200503
Human Fas-associated factor 1, interacting with ubiquitinated proteins and valosin-containing protein, is involved in the ubiquitin-proteasome pathway 송은주,임승희,김은희,김남순,이공주, Molecular and Cellular Biology 200503
Capillary electrophoresis at the omics level: towards systems biology 슈레쉬바브,송은주,바바르,위문형,유영숙, Electrophoresis 200601
Proteomic and metabolomic analysis of HL-1 cardiomyocytes 송은주,유연웅,정병화,정봉철,유영숙, 63rd KSBMB Annual meeting in 2006 200605
Proteomic and Metabolomic analysis of HL-1 cardiomyocytes 송은주,정병화,정봉철,유영숙, The 7th International Conference on Systems Biology 200610
Analysis of calcium related proteins and metabolites in the cardiomyocytes 송은주,정병화,정봉철,유영숙, 19th FAOBMB Seoul Conference 200705
Parallel analysis of calcium related proteins and metabolites 송은주,최만호,정봉철,유영숙, HUPO 6th Annual World Congress 200710
CE at the omics level: towards systems biology - an update 송은주,바바르,오을식,나비울,홍혜민,유영숙, Electrophoresis 200801
Proteasome inhibition induces neurite outgrowth through posttranslational modification of TrkA receptor 송은주,홍혜민,유영숙, The international journal of biochemistry & cell biology 200903
The Prp19 and the Usp4Sart3 Control the Reversible Ubiquitination on the Spliceosome 송은주, 생화학분자생물학회 201001
Proteomic Analysis of the Calcium Modulated Cardiomyocytes 송은주,타누자 다스,유영숙, 생화학분자생물학회 201005
The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome 송은주,Shannon L. Werner,Jakob Neubauer,Frank Stegmeier,Julie Aspden,Donald Rio,J. Wade Harper,Stephen J. Elledge,,Marc W. Kirschner,,Michael Rape, Genes & development 201007
Endothelin-1- and isoproterenol-induced differential protein expression and signaling pathway in HL-1 cardiomyocytes 홍혜민,송은주,오을식,카비르,이철주,유영숙, Proteomics 201101
Nerve growth factor-induced neurite outgrowth is potentiated by stabilization of TrkA receptors 송은주,유영숙, BMB REPORTS 201103
Signaling Pathway Analysis of Cardiac Hypertrophy Using Omics Approach 송은주, 한국응용생명화학회 201104
The potential role of Usp15 in reversible ubiquitination and cell metastasis 타누자 다스,유영숙,송은주, 생화학분자생물학회 201105
Capillary electrophoretic mobility shift assay for binding of DNA with NFAT3, a transcription factor from H9c2 cardiac myoblast cells 박수현,반은미,유영숙,정두수,송은주, CE in the Biotechnology & Pharmaceutical Industries 201110
Growing trend of CE at the omics level: the frontier of systems biology - an update 반은미,박수현,강민정,이현정,송은주,유영숙, Electrophoresis 201201
Potential role of Hsp25 in calcium-modulated cardiomyocytes 타누자 다스,유영숙,임혜원,송은주, Proteomics 201202
Determination of NFAT3, a transcription factor from H9C2 myoblast cells using capillary electrophoresis with dual wavelength laser-induced fluorescence detector 박수현,반은미,채동규,유영숙,송은주, 생화학분자생물학회 (KSBMB) 201205
Potential role of Usp15 in cell cycle regulation 타누자 다스,송은주, 생화학분자생물학회(2012) 201205
Cell cycle regulation by deubiquitinating enzymes 타누자 다스,김은경,송은주, American Society for Cell Biology 201212
Determination of micro-RNA in cardiomyoblast cells using CE with LIF detection 반은미,채동규,송은주, Electrophoresis 201302
Recent developments and applications of capillary electrophoresis with laser-induced fluorescence detection in biological samples 반은미,송은주, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 201306
Enhanced extraction efficiency of miRNA from cells by addition of Triton X-100 반은미,채동규,송은주, Analytical and bioanalytical chemistry 201309
Cholesterol induces cardiac hypertrophy by activating the AKT pathway 이현정,유영숙,이대기,송은주, The Journal of steroid biochemistry and molecular biology 201311
Simultaneous detection of multiple microRNAs for expression profiles of microRNAs in lung cancer cell lines by capillary electrophoresis with dual laser-induced fluorescence 반은미,채동규,송은주, Journal of chromatography A 201311
Quantitative analysis of a ubiquitin-dependent substrate using capillary electrophoresis with dual laser-induced fluorescence 이현정,반은미,김은경,유영숙,이대기,송은주, Electrophoresis 201410
Capillary electrophoresis methods for microRNAs assays 반은미,송은주, Analytica chimica acta 201412
Analysis and applications of nanoparticles in capillary electrophoresis 반은미,유영숙,송은주, Talanta 201508
Proteasome inhibitors attenuated cholesterol-induced cardiac hypertrophy in H9c2 cells 이현정,박진영,김은경,유영숙,송은주, BMB REPORTS 201605
Evaluation of inhibition of miRNA expression induced by anti-miRNA oligonucleotides 채동규,반은미,유영숙,백자현,송은주, Analytical and bioanalytical chemistry 201606
Structural basis for recruiting and shuttling of the spliceosomal deubiquitinase USP4 by SART3 박준규,타누자다스,송은주,김은경, Nucleic acids research 201606
USP15 regulates dynamic protein-protein interactions of the spliceosome through deubiquitination of PRP31 타누자다스,박준규,박진영,김은지,Michael Rape,김은경,송은주, Nucleic acids research 201705
MIR-27a regulates the TGF-beta signaling pathway by targeting SMAD2 and SMAD4 in lung cancer 채동규,Eunmi Ban,유영숙,김은경,Ja-Hyun Baik,송은주, Molecular carcinogenesis 201708
An improvement of miRNA extraction efficiency in human plasma Eunmi Ban,채동규,유영숙,송은주, Analytical and bioanalytical chemistry 201711
USP35 regulates mitotic progression by modulating the stability of Aurora B 박진영,Mi-Sun Kwon,김은경,Hyunsook Lee,송은주, Nature Communications 201802
Deubiquitinase USP35 as a novel mitotic regulator via maintenance of Aurora B stability 박진영,송은주, BMB REPORTS 201806


Patent
Patent
Subject Registration No. Date Country
An improvement of miRNA extraction efficiency in human plasma 10-1880892 20180717 Republic of Korea
Evaluation of anti-miRNA efficiency using capillary electrophoresis with laser-induced fluorescence 10-1783637 20170926 Republic of Korea
The method for quantitative analysis of ubiquitin-proteasome system dependent substrate using capillary electrophoresis with dual laser-induced fluorescence 9766247 20170919 United States of America
The method for quantitative analysis of ubiquitin-proteasome system dependent substrate using capillary electrophoresis with dual laser-induced fluorescence 10-1658638 20160912 Republic of Korea
The regulation of Aurora B stability and mitosis progression by USP35 20160226 Republic of Korea
Inhibition of cholesterol-induced cardiac hypertrophy by proteasome inhibitors 20151005 Republic of Korea
Biomarkers for diagnosing cardiac arrhythmia and method for diagnosis using the same 10-1462006 20141110 Republic of Korea
Enhanced extraction efficiency of miRNA from cells by the addition of Triton X-100 10-1459721 20141103 Republic of Korea
Method for determination of miRNA using capillary electrophoresis with laser induced fluorescence detection for the diagnosis and prognosis of cardiovasular disease 10-1426530 20140729 Republic of Korea
siRNA for inhibition of OTUB1 expression and anticancer composition containing the same 10-1409445 20140612 Republic of Korea
siRNA for inhibition of OTUB1 expression and anticancer composition containing the same 8748592 20140610 United States of America
siRNA for Inhibition of USP15 Expression and Pharmaceutical Composition Containing the same 20140610 United States of America
siRNA for Inhibition of USP15 Expression and Pharmaceutical Composition Containing the same 20140529 Republic of Korea
Capillary electrophoretic mobility shift assay for binding of DNA with NFAT 10-1351334 20140106 Republic of Korea
Biomarkers for diagnosing cardiac arrhythmia and method for diagnosis using the same 10-1331787 20131115 Republic of Korea
Biomarkers for identification of cardiac hypertrophy and the method of identification 10-1296743 20130808 Republic of Korea
Simultaneous detection of multiple miRNAs using capillary electrophoresis with dual laser induced fluorescence detection 20130418 United States of America
Simultaneous detection of multiple miRNAs using capillary electrophoresis with dual laser induced fluorescence detection 20130225 Republic of Korea
Enhanced extraction efficiency of miRNA from cells by the addition of Triton X-100 20130204 United States of America
Method for determination of miRNA using capillary electrophoresis with laser induced fluorescence detection for the diagnosis and prognosis of cardiovasular disease 20121121 United States of America
METHOD TO MEASURE THE PHOSPHORYLATED STAT1 IN CELLS 10-1173027 20120806 Republic of Korea