Research Fields of KIST Professors

research fields list
Name PAN CHEOL-HO
Position(full time/adjunct) Adjunct Professor
KIST School Major Bio-Medical Science and Technology
Division / Center KIST Gangneung Institute of Natural Products / Systems Biotechnology Research Center
Email panc@kist.re.kr
Telephone +82-2-958-3652


Research Field & Research Interest
  • Biochemistry, Agricultural Chemistry, Bioavailability of natural products, Protein-natural product interaction


Research Project
  • Development of novel proteins with photo-reactivity
  • Standardization of protein quality of hEGF and PTD-hEGF
  • Establishment of bioinformatics pipeline for discovering functional materials from marine life resources
  • Development of natural products for treatment and prevention of rheumatoid arthritis through modulating gut microbial community
  • Development and industrialization of high value cosmetic raw materials from marine microalgae
  • Development of noodle product using natural color and study on simulated digestion of the product for demand creation of colored potato
  • test
  • Control and monitoring of bacterial contamination in the culture of Phaeodactylum tricornutum
  • Structural analysis of DWP450
  • Study on the industrialization of fucoxanthin
  • Scientific evaluation of Dendropanax morbifera on biological activities and development of functional food from Dendropanax morbifera
  • 1
  • Evaluation of batch fluctuation of DWP450
  • Identification and isolation of index compound in DM sample
  • Biochemical analysis of sea cucumber
  • Development of high valued garlic product using high hydrostatic pressure process
  • Microencapsulation of mint oil and lactic acid bacteria
  • Study on extraction and bioavailability of natural bioactive oils
  • Characterization of DWP450
  • Development of functional food suppressing macular degenaration from plant resources containing xanthophyll
  • Development of health functional food for anti-hyperlipidemia using Gymnaster koraiensis and Artemisia dubia
  • Development of functional food suppressing macular degenaration from plant resources containing xanthophyll
  • Research on production method of PDRN(polydeoxyribonucleic acid) and PN(polynucleotide) from fish germ cells
  • Development of Medical Instrument for Anti-wrinkles Effect and Production of Polynucleotide from Salmonidae by Pulsed Electric Field Technique
  • Development of novel health food ingredient from Cruciferae species by cutting-edge processing technology


Paper Publication
Paper Publication
Title Author Journal Date Abstract
Structural and function analyses of the global regulatory protein SarA from Staphylococcus aureus Yingfang Liu,Adhar C. Manna,판철호,Irina A. Kriksunov,Daniel J. Thiel,Ambrose L. Cheung,Gongyi Zhang, Proceedings of the National Academy of Sciences of the United States of America 200602
Molecular Cloning of Acidic Class III Chitinase Gene from Rehmannia glutinosa 김수일,판철호, JOURNAL OF CHITIN AND CHITOSAN 200706
Method for screening aldose reductase-specific inhibitor from natural products 송대근,이은하,이주영,정상훈,판철호, 한국응용생명화학회 200710
Mechanistic Study of Cancer Chemopreventive Effects of Korean Seaweeds 이샛별,이재권,이주영,송대근,김민철,이은하,엄병헌,노주원,김영식,판철호, The 9th International Conference on Mechanisms of Antimutagenesis and Anticarcinogenesis 200712
Immunosuppressive Effect of Tectorigenine on Mouse Macrophage Cell Line 판철호,김은선,정상훈,이재권, Experimental Biology 2008 200804
Specific inhibitory effect of some natural products toward aldose reductase 판철호,이은하,이주영,정상훈,송대근, Experimental Biology 2008 200804
Novel extraction technology of bioactive compounds from natural products 차광현,구송이,이동언,판철호, 한국응용생명화학회 200805
Specific Inhibition of Some Natural Products toward Aldose Reductase 송대근,이은하,이주영,정상훈,판철호, 한국응용생명화학회 200805
Cancer Chemopreventive Effects of Korean Seaweeds 이샛별,이재권,이주영,송대근,이은하,엄병헌,노주원,판철호, Proceedings of the 4th KSP-JSP-CCTCNM Joint Symposium on Pharmacognosy 200806
Enzymatic Properties of Recombinant Rehmannia Class III Chitinase Expressed in Bacillus subtilis 판철호,김수일, JOURNAL OF CHITIN AND CHITOSAN 200806
Impact of high hydrostatic pressure on the biological cell membrane and increased leaching of antioxidant substances from Phyllostachys nigra MUNRO (O-juk) leaves 차광현,구송이,판철호, Proceedings of the 4th KSP-JSP-CCTCNM joint symposium on pharmacognosy 200806
Korean Seaweed Extracts Showing Cancer Chemopreventive Effect through the Induction of Phase II Detoxification Enzymes and Anti-inflammatory activities 이샛별,이재권,이은하,이주영,송대근,노주원,정상훈,김형섭,엄병헌,판철호, Proceedings of the 4th International Symposium on the Marine Biotechnology and Advanced Materials 200806
Novel extraction technology of bioactive compounds from marine products 차광현,구송이,판철호, Proceedings of the 4th international symposium on the marine biotechnology and advanced materials 200806
Secretory Expression of Rehmannia Class III Chitinase in Bacillus subtilis 판철호,김수일, Journal of applied biological chemistry 200806
Studies on Aldose Reductase Inhibitor from Natural Products 송대근,이은하,이주영,정상훈,판철호, Proceedings of the 4th KSP-JSP-CCTCNM Joint Symposium on Pharmacognosy 200806
Effect of HHP processing on isothiocyanate production in Brassica vegetables 구송이,차광현,판철호, US-Korea conference on Science, Technology, and Entrepreneurship 200808
Amplification of secondary metabolites in Brassica vegetables by high hydrostatic pressure processing 구송이,차광현,판철호, 2008첨단과학기술전문가회의(Plant Metabolomics as a Tool for Functional Genomics) 200811
Tectorigenin Inhibits IFN-γ/LPS-induced Inflammatory Responses in Murine Macrophage RAW 264.7 Cells 판철호,김은선,정상훈,노주원,이재권, Archives of pharmacal research 200811
Changes in the contents of sulforaphane in Brassica vegetabels after High Hydrostatic Pressure (HHP) process 구송이,차광현,판철호, 한국응용생명화학회 200904
Amplification of sulforaphane in Brassica vegetables after high hydrostatic pressure (HHP) process 구송이,차광현,판철호, 한국식품과학회 200905
Anti-inflammatory Mechanism of Seaweeds in Murine Macrophage 판철호,김은선,엄병헌,이재권, Food science and biotechnology 200906
Extraction of bioactive carotenoids from chlorella using pressurized hot liquids and high hydrostatic pressure 차광현,구송이,이동언,판철호, Institute of Food Technologists 200906
Inhibitory Effects of Korean Local Plant Extracts on Aldo-keto reductase 1B10 (AKR1B10) 이주영,송대근,정상훈,노주원,손진기,판철호, 한국응용생명화학회 200910
Optimization of Pressurized Liquid Extraction of Carotenoids and Chlorophylls from Chlorella vulgaris 차광현,이희주,구송이,송대근,이동언,판철호, 한국응용생명화학회 200910
Inhibitory Effects of 23 Korean Local Plant Extracts on Aldo-keto reductase family 1 B10 (AKR 1 B10) 이주영,송대근,정상훈,김종환,안수용,노주원,판철호, 생약학회지 200910
Carotenoids from chlorella: their antiproliferative activity and production 차광현,판철호, International Symposium on Seafood Processing Technology and Safety Control System 200911
Inhibitory Effects of 3,5-O-Dicaffeoyl-epi-quinic Acid from Gymnaster koraiensis on AKR1B10 이주영,송대근,이은하,정상훈,노주원,차광현,판철호, 한국응용생명화학회지 = JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY 200912
Antioxidant and Aldo-keto reductase family 1 B10 Inhibition Activities of Korean Local Plant Extracts 판철호,이주영,송대근,김종환,안수용,배덕성,김영훈,이재권, Journal of applied biological chemistry. 200912
Optimization of Pressurized Liquid Extraction of Carotenoids and Chlorophylls from Chlorella vulgaris 차광현,이희주,구송이,송대근,이동언,판철호, Journal of agricultural and food chemistry 201001
Effect of Pressurized Liquids on Extraction of Antioxidants from Chlorella vulgaris 차광현,강석우,김철영,엄병헌,나예림,판철호, Journal of agricultural and food chemistry 201004
Inhibitory effects of polyphenols isolated from Rhus verniciflua on Aldo-keto reductase family 1 B10 송대근,이주영,이은하,정상훈,노주원,차광현,구송이,판철호, BMB REPORTS 201004
Inhibitory effects of natural products on Aldo-keto reductase family 1 B10 이주영,송대근,정상훈,노주원,손진기,판철호, The13th international symposium on the efficient application and preservation of marine biological resources 201006
RPSA Degradation May Mediate Apoptosis in HeLa Cell by Parkin Overexpression 송대근,이인수,김윤석,판철호, The 13th International Symposium on the Efficient Application and Preservation of Marine Biological Resources 201006
Effect of Agarase Signal Peptide from Agarivorans albus YKW-34 on Protein Secretion in Escherichia coli 이주영,송대근,손진기,판철호, Journal of applied biological chemistry. 201006
Apoptosis in HeLa cell by Parkin overexpression might be mediated through RPSA degradation 송대근,이인수,김윤석,판철호, 한국응용생명화학회 201008
Optimization of pressurized liquid extraction of zeaxanthin from chlorella ellipsoidea 구송이,차광현,송대근,판철호, 한국응용생명화학회 201008
Inhibitory effects of dicaffeoylquinic acids from Artemisia dubia on aldo-keto reductase family 1B10 이희주,이주영,김상민,노주원,정상훈,송대근,김철영,판철호, 한국응용생명화학회지 = JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY 201012
Amplification of Sulforaphane Content in Red Cabbage by Pressure and Temperature Treatments 구송이,차광현,송대근,정동화,판철호, 한국응용생명화학회지 = JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY 201104
Inhibitory effects of phlorofucofuroeckol-A isolated from Eisenia bicyclis on aldo-keto reductase family 1 B1 and 1 B10 이주영,김상민,송대근,정우석,차광현,엄병헌,손진기,판철호, 한국응용생명화학회 춘계학술대회 201104
Effect of Chlorella Pulverization by Microfluidization on Lutein Micellization in Vitro and Uptake by Caco-2 Cells 차광현,이주영,송대근,정우석,김상민,이동언,판철호, 한국식품과학회 201106
Hepatoprotective effect of flavonoid glycosides from Lespedeza cuneata against oxidative stress induced by tert-butyl heperoxide 김상민,강경수,조은혜,정유진,노주원,엄병헌,판철호, Phytotherapy research : PTR 201107
중국 수출을 위한 고품질 건해삼 제품 개발 판철호, 제1회 한국산업융합 학술대회 201107
Amplification of allyl isothiocyanate in red cabbage using high hydrostatic pressure treatment 구송이,차광현,송대근,정동화,이동언,판철호, JOURNAL OF MEDICINAL PLANTS RESEARCH 201108
Effect of Microfluidization on in Vitro Micellization and Intestinal Cell Uptake of Lutein from Chlorella vulgaris 차광현,이주영,송대근,김상민,이동언,전진영,판철호, Journal of agricultural and food chemistry 201108
Biological activities of alcohol extracts of some plants collected from Saudi Arabia 이주영,배덕성,김영훈,이재권,Hossam Abdallah,Essam Abdel-Sattar,판철호, 2011 International Symposium & Annual Meeting of the KSABC 201110
Effect of Chlorella Microfluidization on Lutein Bioavailability 차광현,이주영,송대근,정우석,김상민,이동언,판철호, 제3회 한러 바이오 산업기술 포럼 201110
Hepatoprotective Effect of Flavonoid Glycosides from Lespedeza cuneata against Oxidative Stress Induced by tert-Butyl Hyperoxide 정유진,김상민,강경수,조은혜,노주원,엄병헌,판철호, 제3회 한러 바이오 산업기술 포럼 201110
Phlorofucofuroeckol-A, a promising dual inhibitor of aldo-keto reductase family 1 B1 and 1 B10 이주영,김상민,송대근,정우석,차광현,엄병헌,손진기,판철호, 제3회 한러 바이오 산업기술 포럼 201110
클로렐라 루테인의 산업화 연구 판철호, 천연물 신소재 발굴 및 실용화를 위한 산학연 심포지움 201111
A Potential Commercial Source of Fucoxanthin Extracted from the Microalga Phaeodactylum tricornutum 김상민,정유진,권오남,차광현,엄병헌,정동화,판철호, Applied biochemistry and biotechnology 201204
Effect of microfluidization on bioaccessibility of carotenoids from chlorella ellipsoidea during simulated digestion 강경수,차광현,구송이,송대근,노주원,판철호, Experimental biology 2012 201204
Inhibititory Effect of Gastrointestinal Lipolysis by Green Tea, Coffee, and Gomchui (Ligularia fischeri) Tea during Simulated Digestion 강경수,차광현,송대근,김상민,이은하,이희주,판철호, Experimental biology 2012 201204
Mint oil Encapsulation with Alginate/pectin using Co-axial Electrospray system 구송이,차광현,송대근,판철호, 11th International Hydrocolloids conference 201205
미세조류 카로티노이드의 생이용성 연구 판철호,차광현, 제19회 광전자 및 광통신 학술회의 201205
Mint oil Encapsulation with Alginate/Pectin using Co-axial Electrospray System 구송이,차광현,송대근,판철호, 한국식품과학회 201206
Inhibition of Gastrointestinal Lipolysis by Green Tea, Coffee, and Gomchui (Ligularia fischeri) Tea Polyphenols during Simulated Digestion 차광현,송대근,김상민,판철호, Journal of agricultural and food chemistry 201207
Fucoxanthin as a Major Carotenoid in Isochrysis aff. galbana: Characterization of Extraction for Commercial Application 김상민,강석우,권오남,정동화,판철호, 한국응용생명화학회지 = JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY 201208
Optimization of pressurized liquid extraction of zeaxanthin from Chlorella ellipsoidea 구송이,차광현,송대근,정동화,판철호, Journal of applied phycology 201208
Secretome Analysis of Gymnasterkoreayne B Treated HCT116 Cells 송대근,강경수,이은하,정상훈,노주원,판철호, 한국질량분석학회 2012여름정기학술대회 201208
Effect of Microfluidization on Bioaccessibility of Carotenoids from Chlorella ellipsoidea during Simulated Digestion 차광현,구송이,송대근,판철호, Journal of agricultural and food chemistry 201209
Increased Sulforaphane Concentration in Brussels Sprout Following High Hydrostatic Pressure Treatment 구송이,차광현,송대근,이동언,판철호, 한국응용생명화학회지 = JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY 201210
Bioaccessibilty of Natural Products during Simulated Digestion 차광현,송대근,구송이,판철호, 2012 International Symposium and Annual Meeting of the KSABC 201211
Phlorofucofuroeckol-A, a Potent Inhibitor of Aldo-keto Reductase Family 1 Member B10, from the Edible Brown Alga Eisenia bicyclis 이주영,김상민,정우석,송대근,엄병헌,손진기,판철호, 한국응용생명화학회지 = JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY 201212
Analysis of Carotenoids in 25 Indigenous Korean Coral Extracts 김상민,강석우,이은아,서은경,송준임,판철호, Journal of applied biological chemistry 201303
Bioaccessibility of Polyphneols from Youngia denticulata, edible wile vegetable, during Simulated Digestion 이희주,차광현,노주원,판철호, 2013 한국응용생명화학회 국제심포지움 201306
Fucoxanthin Production from Marine Organisms for Commercial and Industrial Applications 김상민,엄병헌,판철호, 2013 한국응용생명화학회 국제심포지움 201306
Identification of Anthocyanins by LC-MS and Hepatoprotective Effects of Anthocyanin-Rich Fractions from the Colored Potatoes, 'Hongyoung' and 'Jayoung' Cultivars 김상민,강경수,하인수,엄재인,노주원,정진철,권오근,남정환,판철호, 2013 한국응용생명화학회 국제심포지움 201306
Crystal Structure and Substrate Specificity of D-Galactose-6-Phosphate Isomerase Complexed with Substrates 정우석,Raushan Kumar Singh,이정걸,판철호, PLoS ONE 201308
Microfluidization Enhances Absorption of Lutein from Chlorella vulgaris by Caco-2 Intestinal Cells and Adult Rats 차광현,정상훈,안홍열,강석우,김경아,판철호, 한국식품과학회 201308
A Monoclonal Antibody Against the Human SUMO-1 Protein Obtained by Immunization with Recombinant Protein and CpG-DNA-liposome Complex Dongbum Kim,이주영,송대근,Sanghoon Kwon,Younghee Lee,판철호,Hyung-Joo Kwon, MONOCLONAL ANTIBODIES IN IMMUNODIAGNOSIS AND IMMUNOTHERAPY 201310
Inhibitory effect of Thuja orientalis on aldo-keto reductase family 1 B10 이주영,정우석,송대근,이은하,정상훈,이재권,판철호, 과학교육연구논총 201311
Quantification of antioxidant compounds from colored potatoes, 'Hongyoung' and 'Jayoung' cultivars and their protective activity on human hepatoma HepG2 cell 김상민,강경수,하인수,노주원,남정환,조지홍,권오근,정진철,이재권,판철호, 과학교육연구논총 201311
Parkin Induces Upregulation of 40S Ribosomal Protein SA and Posttranslational Modification of Cytokeratins 8 and 18 in Human Cervical Cancer Cells 송대근,김윤석,정병철,이기종,판철호, Applied biochemistry and biotechnology 201312
Bioavailability of Chlorella carotenoids 차광현,송대근,구송이,판철호, The 2nd International Conference on Food and Applied Bioscience 201402
Microencapsulation of peppermint oil in an alginate-pectin matrix using a coaxial electrospray system 구송이,차광현,송대근,정동화,판철호, International Journal of Food Science and Technology 201403
Secretome Profiling Reveals the Signaling Molecules of Apoptotic HCT116 Cells Induced by the Dietary Polyacetylene Gymnasterkoreayne B 강경수,송대근,이은하,이경미,박영균,정상훈,판철호,노주원, Journal of agricultural and food chemistry 201403
A dietary polyacetylene, Gymnasterkoreayne B, induces both intrinsic and extrinsic pathway of apoptosis through the signaling molecules revealed by secretome profiling 송대근,강경수,이은하,정상훈,판철호,노주원, Experimental biology 2014 201404
Bioavailability of Hydroxycinnamic Acids from Crepidiastrum denticulatum Using Simulated Digestion and Caco-2 Intestinal Cells 이희주,차광현,김철영,노주원,판철호, Journal of agricultural and food chemistry 201406
Digestive Stability, Bioaccessibility, and Permeability of Hydroxycinnamic Acids from Crepidiastrum denticulata Using Simulated Digestion and Caco-2 Intestinal Cells 이희주,차광현,노주원,판철호, 2014년도 한국응용생명화학회 국제학술대회 201406
Bioavailability of anthocyanins from red and purple potatoes under simulated gastrointestinal digestion 구송이,차광현,김상민,판철호, 한국식품과학회지 201408
Characterization and stability of fucoxanthin-nanoliposome composed of lecithin 구송이,목일균,김상민,판철호, 한국식품과학회지 201408
Characterization of curcumin-loaded nanoparticles composed of phosphatidylcholine and β-cyclodextrin 구송이,김다혜,판철호, 한국식품과학회지 201408
Evaluating the in vitro bioaccessibility of isoflavones (aglycones, non-conjugated glucosides, and conjugated glucosides) from different soy products under simulated gastrointestinal digestion 강석우,이은하,차광현,엄병헌,판철호, Planta medica 201409
Bioavailability of Ginsenosides from White and Red Ginsengs in the Simulated Digestion Model 김은옥,차광현,이은하,김상민,최상원,판철호,엄병헌, Journal of agricultural and food chemistry 201410
Characterization of Curcumin-loaded Nanoparticles for Mucoadhesive Applications 구송이,김다혜,판철호, 12th International Congress on Engineering and Food (ICEF12) 201506
Transformation of the Diatom Phaeodactylum tricornutum with its Endogenous (E)-4-Hydroxy-3-methylbut-2-enyl Diphosphate Reductase Gene 신복규,정유진,김상민,판철호, Journal of Applied Biological Chemistry 201509
Combinatorial treatment with amentoflavone and doxorubicin induces synergistic anticancer effect in A549 and NCI-H460 human lung cancer cells 정유진,이은하,정우석,판철호,강경수, 2016년도 한국응용생명화학회 국제학술대회 201606
Evaluation of bioaccessibility of fucoxanthin from sea algae using simulated digestion 차광현,김상민,이은하,강경수,판철호, 2016년도 한국응용생명화학회 국제학술대회 201606
The Role of Isopentenyl Pyrophosphate Reductase and Geranylgeranyl Pyrophosphate Synthase on Pigment Biosynthesis in Phaeodactylum tricornutum 신복규,정유진,엄재인,김상민,판철호, 2016년도 한국응용생명화학회 국제학술대회 201606
Production of Recombinant EGF in Escherichia coli 판철호,김윤미,Woo Seok Jung,Kwang Won Hong, 2016년도 한국응용생명화학회 국제학술대회 201606
Regulation of isoprenoid biosynthetic pathway in Phaeodactylum tricornutum depending on difference environments 판철호,김상민,신복규,정유진, 2016년도 한국응용생명화학회 국제학술대회 201606
Cloning of a novel endogenous promoter for foreign gene expression in Phaeodactylum tricornutum 에르데네돌고르,신복규,나즈물 후다,김다혜,이은하,송대근,김윤미,김상민,판철호, 한국응용생명화학회지 = JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY 201612
Expression, phosphorylation, localization, and microtubule binding of tau in colorectal cell lines 나즈물 후다,김다혜,에르데네돌고르,김윤석,판철호, 한국응용생명화학회지 = JOURNAL OF THE KOREAN SOCIETY FOR APPLIED BIOLOGICAL CHEMISTRY 201612
The Protective Effect of Antioxidant Enriched Fractions from Colored Potatoes Against Hepatotoxic Oxidative Stress in Cultured Hepatocytes and Mice 김다혜,김명석,오상빈,이경미,김상민,노주원,윤원병,강경수,판철호, Journal of food biochemistry 201702
AKR1B10-inhibitory Selaginella tamariscina extract and amentoflavone decrease the growth of A549 human lung cancer cells in vitro and in vivo 정유진,이은하,이창근,이기종,정우석,최용수,판철호,강경수, Journal of ethnopharmacology 201704
Comparison of static and dynamic in vitro digestion models to estimate the bioaccessibility of lutein in lutein-rich foods 이은하,차광현,김상민,박우태,윤계윤,진종범,판철호, 2017 한국응용생명화확회 천연물분과 심포지엄 201709
Assay for Phosphorylation and Microtubule Binding Along with Localization of Tau Protein in Colorectal Cancer Cells 나즈물 후다,에르데네돌고르,판철호, Journal of visualized experiments : JoVE 201710
미세조류 Phaeodactylum tricornutum으로부터 푸코잔틴 생합성 증대 방법 연구 김상민,엄재인,트랑 티 부옹,정유진,신복규,권벼리,판철호, 한국해양바이오학회 201711


Patent
Patent
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