Research Fields of KIST Professors

research fields list
Name Hur, Eun-Mi
Position(full time/adjunct) Adjunct Professor
KIST School Major Bio-Medical Science and Technology
Division / Center President / Convergence Research Center for Diagnosis, Treatment and Care System of Dementia
Email ehur@kist.re.kr
Telephone +82-2-958-6856


Research Field & Research Interest
  • Biology, Molecular neurons, biology, Neural development and regeneration


Research Project
  • Investigation of axon re/degeneration by regulation of MT PTMs
  • Development of animal models for neurodevelopmental disorders and TRAP-based identification of biomarkers for neurodevelopmental disorders
  • Regulation of axon re- and degeneration by microtubule PTMs
  • Investigation of axon re/degeneration by regulation of microtubule post-translational modifications
  • Establishment of 3D in vitro myelination model system & Investigation of cellular mechanisms for de/regeneration
  • 3D in vitro reconstruction of neuron-glia network towards understanding myelination and de/regeneration of axons
  • Role and regulation of GSK3 during neural development and regeneration


Paper Publication
Paper Publication
Title Author Journal Date Abstract
Nongenomic inhibition of catecholamine secretion by 17beta-estradiol in PC12 cells Youn-Jae Kim,허은미,Tae-Ju Park,Kyong-Tai Kim, Journal of neurochemistry 200006
Coupling of L-type voltage-sensitive calcium channels to P2X(2) purinoceptors in PC-12 cells 허은미,Tae-Ju Park,Kyong-Tai Kim, American journal of physiology. Cell physiology 200105
G protein-coupled receptor signalling and cross-talk: achieving rapidity and specificity 허은미,Kyong-Tai Kim, Cellular signalling 200205
Sensitization of epidermal growth factor-induced signaling by bradykinin is mediated by c-Src. Implications for a role of lipid microdomains 허은미,Yong-Soo Park,Byoung Dae Lee,Il Ho Jang,Hyeon Soo Kim,Tae-Don Kim,Pann-Ghill Suh,Sung Ho Ryu, Kyong-Tai Kim, The Journal of biological chemistry 200402
Junctional membrane inositol 1,4,5-trisphosphate receptor complex coordinates sensitization of the silent EGF-induced Ca2+ signaling 허은미,Yong-Soo Park,Yang Hoon Huh, Seung Hyun Yoo,Kyung-Chul Woo,Bo-Hwa Choi,Kyong-Tai Kim, The Journal of cell biology 200505
A role of local signalling in the establishment and maintenance of the asymmetrical architecture of a neuron 허은미,Kyong-Tai Kim, Journal of neurochemistry 200701
GSK3 signalling in neural development 허은미,Feng-Quan Zhou, Nature Reviews Neuroscience 201008
Engineering neuronal growth cones to promote axon regeneration over inhibitory molecules 허은미,In Hong Yang,Deok-Ho Kim,Justin Byun,Saijilafu,Wen-Lin Xu,Philip R. Nicovich,Raymond Cheong,Andre Levchenko,Nitish Thakor,Feng-Quan Zhou, Proceedings of the National Academy of Sciences of the United States of America 201103
GSK3 controls axon growth via CLASP-mediated regulation of growth cone microtubules 허은미,Saijilafu,Byoung Dae Lee,Seong-Jin Kim,Wen-Lin Xu,Feng-Quan Zhou, Genes & development 201109
Growing the growth cone: remodeling the cytoskeleton to promote axon regeneration 허은미,Saijilafu,Feng-Quan Zhou, TRENDS IN NEUROSCIENCES 201203
Slit2 Inactivates GSK3b to Signal Neurite Outgrowth Inhibition 변희준,김보택,김윤태,Zhongxian Jiao,허은미,Feng-Quan Zhou, PLoS ONE 201212
Understanding microtubule dynamics during neural development and regeneration 허은미, 한국뇌신경과학회 201309
PI3K-GSK3 signalling regulates mammalian axon regeneration by inducing the expression of Smad1 Saijilafu,허은미,Chang-Mei Liu,Zhongxian Jiao,Wen-Lin Xu,Feng-Quan Zhou, Nature Communications 201310
Growing the growth cone: remodeling the cytoskeletal components to control axon growth and regeneration 허은미, 한일신호전달심포지움 201311
Microtubule-Targeting Agents Enter the Central Nervous System (CNS): Double-edged Swords for Treating CNS Injury and Disease 허은미,Lee, Byoung Dae, International neurourology journal. 201412
Inflammatory signals induce the expression of tonicity-responsive enhancer binding protein (TonEBP) in microglia Ga Ram Jeong,임선경,Yun-Hee Bae,Eun Su Park,Byung Kwan Jin ,Hyug Moo Kwon,Beom-Joon Lee,Youngmin Bu ,허은미,Byoung Dae Lee, Journal of neuroimmunology 201606
Effects of Microtubule Stabilization by Epothilone B Depend on the Type and Age of Neurons 장은혜,심애리,임선경,허은미, Neural Plasticity 201611
Anisotropically organized three-dimensional culture platform for reconstruction of a hippocampal neural network 김소현,임선경,오수진,정소현,윤의성,이창준,최낙원,허은미, Nature Communications 201702
Functional Characterization of Resting and Adenovirus-Induced Reactive Astrocytes in Three-Dimensional Culture 우준성,임선경,전희정,정순영,오수진,최낙원,이창준,허은미, Experimental Neurobiology 201706
Differential roles of glycogen synthase kinase 3 subtypes alpha and beta in cortical development Yan-Xia Ma,Xiu-li Wang, Jian-quan Chen,Bin Li,허은미,Saijilafu, Frontiers in Molecular Neuroscience 201711


Patent
Patent
Subject Registration No. Date Country
고주파를 이용한 인체의 피하지방 분해 장치 Republic of Korea
도파관 안테나를 이용한 하지정맥류 치료 장치 Republic of Korea
Apparatus for brain stimulation using microwave and operating method thereof 10-1772663 20170823 Republic of Korea
BODY STIMULATING STRUCTURE COMPRISING COIL 20170809 United States of America
희돌기아교세포 특이적 유전자 발현 조절 벡터 20170728 Republic of Korea
METHOD FOR INDUCING REACTIVE ASTROCYTE AND THREE DIMENSIONAL CELL STRUCTURE CONTAINING ASTROCYTE 20170628 Republic of Korea
METHOD FOR INCUBATION OF MOTOR NEURON IN VITRO AND INCUBATION KIT THEREOF 10-1748631 20170613 Republic of Korea
Transcranial magnetic stimulation apparatus for small animal 10-1733589 20170428 Republic of Korea
SYSTEM AND METHOD FOR EFFECTING HYPERTHERMIC TREATMENT USING APPLICATOR 20170220 PCT
Transcranial magnetic stimulation apparatus for small animal 20170220 PCT
omposition of medium for glial cell cultivation of mouse and method of mouse glial cell differentiation 10-1705698 20170206 Republic of Korea
희소돌기아교세포 분화용 조성물 및 이를 이용한 희소돌기아교세포 분화방법 20170125 Republic of Korea
뇌염증 진단용 바이오마커 및 이의 용도 20170113 Republic of Korea
COMPOSITION CONTAINING COENZYME Q10 TO PROMOTE INCUBATION OF MOTOR NEURON IN VITRO 10-1695429 20170105 Republic of Korea
운동 뉴런의 생체외 배양 방법 및 운동 뉴런 배양용 조성물 20170103 Republic of Korea
Apparatus for brain stimulation using microwave and operating method thereof 20161110 PCT
APPARATUS AND METHOD FOR TREATING PAIN 10-1653225 20160826 Republic of Korea
BODY STIMULATING STRUCTURE COMPRISING COIL 20160811 Republic of Korea
SYSTEM AND METHOD FOR EFFECTING HYPERTHERMIC TREATMENT USING APPLICATOR 20160323 Republic of Korea
Open ended MEMS Tetrode for in-vivo neural signal detection 8682412 20140325 United States of America
Open ended MEMS Tetrode for in-vivo neural signal detection 10-1310767 20130913 Republic of Korea
통증감소를 위한 시상의 전기자극장치 1137525 20120410 Republic of Korea