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KIST 한국과학기술연구원 Korea Institute of Science and Technology

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Title KIST's Persons of the Month: Dr. Ae Nim Pae and Dr. Yun Kyung Kim (2020.02.29)
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Date 2020-02-29 Hits 965

KIST's Persons of the Month: Dr. Ae Nim Pae and Dr. Yun Kyung Kim

 

On January 28, 2020, Dr. Ae Nim Pae and Dr. Yun Kyung Kim from KIST’s Convergence Research Center for Dementia DTC received the KIST Person of the Month Award for their achievements.

 

Dr. Ae Nim Pae, the Head of KIST’s Convergence Research Center for Dementia DTC, and principal researcher Dr. Yun Kyung Kim have developed candidate materials for the treatment of dementia using the Tau protein anti-clogging method.

 

Researchers at KIST have established cellular and animal models which enable oligomer formation to be monitored during the early, coagulative stages of a Tau protein, one of the main causes of Alzheimer’s dementia. Through drug screening and optimization derived from those models, KIST researchers were able to determine which materials excelled in efficacy and safety.

 

In order to develop the technology as a competitive clinical candidate, KIST transferred it to Dong-A ST, a major pharmaceutical company in Korea, for a down payment of KRW 1 billion (milestone set based on development and clinical progress), and signed an MOU on the 11th of December, 2019 for carrying out joint clinical research and development.

 

Dr. Ae Nim Pae, who majored in the synthesis of drugs, conducted the design and synthesis of new compounds, while Dr. Yun Kyung Kim established an evaluation system for Tau protein coagulation efficacy based on close cooperative research to derive the top high-performing materials for dementia treatment.

 

KIST’s Person of the Month Award recognizes and rewards high achievers who contribute to the Institute in creative, innovative ways. Winners are selected by the Reward Deliberation Committee. This time, Dr. Ae Nim Pae and Dr. Yun Kyung Kim were both selected in recognition of their research achievements.

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